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Synthesis and Characterization of Store-Operated Calcium Entry Inhibitors Active in the Submicromolar Range

The store-operated calcium entry, better known as SOCE, forms the main Ca(2+) influx pathway in non-excitable cells, especially in leukocytes, where it is required for cell activation and the immune response. During the past decades, several inhibitors were developed, but they lack specificity or ef...

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Detalles Bibliográficos
Autores principales: Le Guilcher, Camille, Luyten, Tomas, Parys, Jan B., Pucheault, Mathieu, Dellis, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767506/
https://www.ncbi.nlm.nih.gov/pubmed/33371518
http://dx.doi.org/10.3390/ijms21249777