Synthesis of novel indolo[3,2-c]isoquinoline derivatives bearing pyrimidine, piperazine rings and their biological evaluation and docking studies against COVID-19 virus main protease

A series of hybrid indolo[3,2-c]isoquinoline (δ-carboline) analogs incorporating two pyrimidine and piperizine ring frameworks were synthesized. Intending biological activities and SAR we propose replacements of fluorine, methyl and methoxy of synthetic compounds for noteworthy antimicrobial, antiox...

Descripción completa

Detalles Bibliográficos
Autores principales: Verma, Vaijinath A., Saundane, Anand R., Meti, Rajkumar S., Vennapu, Dushyanth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767577/
https://www.ncbi.nlm.nih.gov/pubmed/33390613
http://dx.doi.org/10.1016/j.molstruc.2020.129829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767577/
https://www.ncbi.nlm.nih.gov/pubmed/33390613
http://dx.doi.org/10.1016/j.molstruc.2020.129829

Ejemplares similares