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Synthesis of novel indolo[3,2-c]isoquinoline derivatives bearing pyrimidine, piperazine rings and their biological evaluation and docking studies against COVID-19 virus main protease

A series of hybrid indolo[3,2-c]isoquinoline (δ-carboline) analogs incorporating two pyrimidine and piperizine ring frameworks were synthesized. Intending biological activities and SAR we propose replacements of fluorine, methyl and methoxy of synthetic compounds for noteworthy antimicrobial, antiox...

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Detalles Bibliográficos
Autores principales:	Verma, Vaijinath A., Saundane, Anand R., Meti, Rajkumar S., Vennapu, Dushyanth R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767577/ https://www.ncbi.nlm.nih.gov/pubmed/33390613 http://dx.doi.org/10.1016/j.molstruc.2020.129829

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