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Retinal homeostasis and metformin-induced protection are not affected by retina-specific Pparδ knockout

Peroxisome proliferator-activated receptors (PPARs) are a family of three nuclear hormone receptors (PPARα, PPARδ, and PPARγ) that are known to regulate expression of lipid metabolism and oxidative stress genes. Given their role in reducing oxidative stress in a variety of tissues, these genes are l...

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Detalles Bibliográficos
Autores principales: Xu, Lei, Brown, Emily E., Santiago, Clayton P., Keuthan, Casey J., Lobanova, Ekaterina, Ash, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767733/
https://www.ncbi.nlm.nih.gov/pubmed/32863184
http://dx.doi.org/10.1016/j.redox.2020.101700