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Microenvironment Remodeling and Subsequent Clinical Implications in Diffuse Large B-Cell Histologic Variant of Richter Syndrome

INTRODUCTION: Richter Syndrome (RS) is defined as the development of an aggressive lymphoma in the context of Chronic Lymphocytic Leukemia (CLL), with a Diffuse Large B-Cell Lymphoma (DLBCL) histology in 95% cases. RS genomic landscape shares only a few features with de novo DLBCLs and is marked by...

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Detalles Bibliográficos
Autores principales: Augé, Hélène, Notarantonio, Anne-Béatrice, Morizot, Romain, Quinquenel, Anne, Fornecker, Luc-Matthieu, Hergalant, Sébastien, Feugier, Pierre, Broséus, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767850/
https://www.ncbi.nlm.nih.gov/pubmed/33381116
http://dx.doi.org/10.3389/fimmu.2020.594841