The Convergence of Alpha-Synuclein, Mitochondrial, and Lysosomal Pathways in Vulnerability of Midbrain Dopaminergic Neurons in Parkinson’s Disease

Parkinson’s disease (PD) is the second most common neurodegenerative disease, characterized by progressive bradykinesia, rigidity, resting tremor, and gait impairment, as well as a spectrum of non-motor symptoms including autonomic and cognitive dysfunction. The cardinal motor symptoms of PD stem fr...

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Detalles Bibliográficos
Autores principales: Minakaki, Georgia, Krainc, Dimitri, Burbulla, Lena F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767856/
https://www.ncbi.nlm.nih.gov/pubmed/33381501
http://dx.doi.org/10.3389/fcell.2020.580634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767856/
https://www.ncbi.nlm.nih.gov/pubmed/33381501
http://dx.doi.org/10.3389/fcell.2020.580634

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