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TRPV4 Plays a Role in Matrix Stiffness-Induced Macrophage Polarization

Phenotypic polarization of macrophages is deemed essential in innate immunity and various pathophysiological conditions. We have now determined key aspects of the molecular mechanism by which mechanical cues regulate macrophage polarization. We show that Transient Receptor Potential Vanilloid 4 (TRP...

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Detalles Bibliográficos
Autores principales: Dutta, Bidisha, Goswami, Rishov, Rahaman, Shaik O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767862/
https://www.ncbi.nlm.nih.gov/pubmed/33381111
http://dx.doi.org/10.3389/fimmu.2020.570195