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Chemical-Induced Cleft Palate Is Caused and Rescued by Pharmacological Modulation of the Canonical Wnt Signaling Pathway in a Zebrafish Model

Cleft palate is one of the most frequent birth defects worldwide. It causes severe problems regarding eating and speaking and requires long-term treatment. Effective prenatal treatment would contribute to reducing the risk of cleft palate. The canonical Wnt signaling pathway is critically involved i...

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Detalles Bibliográficos
Autores principales: Narumi, Rika, Liu, Shujie, Ikeda, Naohiro, Morita, Osamu, Tasaki, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767894/
https://www.ncbi.nlm.nih.gov/pubmed/33381503
http://dx.doi.org/10.3389/fcell.2020.592967