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Early-Life Stress Alters Synaptic Plasticity and mTOR Signaling: Correlation With Anxiety-Like and Cognition-Related Behavior

Early-life stress (ELS) predisposes individuals to psychiatric disorders, including anxiety and depression, and cognitive impairments later in life. However, the underlying molecular mechanisms are not completely understood. Developmental deficits in hippocampal synaptic plasticity are among the pri...

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Detalles Bibliográficos
Autores principales: Wang, Anfeng, Zou, Xiaojuan, Wu, Jiajia, Ma, Qingyu, Yuan, Naijun, Ding, Fengmin, Li, Xiaojuan, Chen, Jiaxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767996/
https://www.ncbi.nlm.nih.gov/pubmed/33381149
http://dx.doi.org/10.3389/fgene.2020.590068