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Cytokine and Chemokine Signals of T-Cell Exclusion in Tumors

The success of cancer immunotherapy in solid tumors depends on a sufficient distribution of effector T cells into malignant lesions. However, immune-cold tumors utilize many T-cell exclusion mechanisms to resist immunotherapy. T cells have to go through three steps to fight against tumors: trafficki...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Guan, Xin-yuan, Jiang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768018/
https://www.ncbi.nlm.nih.gov/pubmed/33381115
http://dx.doi.org/10.3389/fimmu.2020.594609