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Characterization of Genome-Wide DNA Methylation and Hydroxymethylation in Mouse Arcuate Nucleus of Hypothalamus During Puberty Process

Background: Pulsatile pituitary gonadotropin secretion governed by hypothalamic gonadotropin-releasing hormone (GnRH) is essential for the pubertal onset. The epigenetic mechanism underlying the activation of GnRH-dependent regulatory axis in hypothalamus remains elusive. This study aims to explore...

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Detalles Bibliográficos
Autores principales: Shen, Yihang, Zhou, Shasha, Zhao, Xiaodong, Li, Hua, Sun, Jielin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768033/
https://www.ncbi.nlm.nih.gov/pubmed/33381157
http://dx.doi.org/10.3389/fgene.2020.626536