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Resolving the Paradox of Colon Cancer Through the Integration of Genetics, Immunology, and the Microbiota

While colorectal cancers (CRC) are paradigmatic tumors invaded by effector memory lymphocytes, the mechanisms accounting for the relative resistance of MSI negative CRC to immunogenic cell death mediated by oxaliplatin and immune checkpoint inhibitors has remained an open conundrum. Here, we propose...

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Detalles Bibliográficos
Autores principales: Fidelle, Marine, Yonekura, Satoru, Picard, Marion, Cogdill, Alexandria, Hollebecque, Antoine, Roberti, Maria Paula, Zitvogel, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768083/
https://www.ncbi.nlm.nih.gov/pubmed/33381121
http://dx.doi.org/10.3389/fimmu.2020.600886