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The GluA1 AMPAR subunit is necessary for hedonic responding but not hedonic value in female mice

The GluA1 subunit of the AMPA receptor has been implicated in anhedonia. Mice that lack GluA1 (Gria1 knockout mice) show reduced lick cluster size, a measure of palatability in feeding behaviour. This deficit may reflect a role for GluA1 in encoding the hedonic value of palatable substances or inste...

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Detalles Bibliográficos
Autores principales: Strickland, Jasmin A., Austen, Joseph M., Sprengel, Rolf, Sanderson, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768090/
https://www.ncbi.nlm.nih.gov/pubmed/33058902
http://dx.doi.org/10.1016/j.physbeh.2020.113206