Improving Transgenesis Efficiency and CRISPR-Associated Tools Through Codon Optimization and Native Intron Addition in Pristionchus Nematodes

A lack of appropriate molecular tools is one obstacle that prevents in-depth mechanistic studies in many organisms. Transgenesis, clustered regularly interspaced short palindromic repeats (CRISPR)-associated engineering, and related tools are fundamental in the modern life sciences, but their applic...

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Detalles Bibliográficos
Autores principales: Han, Ziduan, Lo, Wen-Sui, Lightfoot, James W., Witte, Hanh, Sun, Shuai, Sommer, Ralf J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768246/
https://www.ncbi.nlm.nih.gov/pubmed/33060138
http://dx.doi.org/10.1534/genetics.120.303785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768246/
https://www.ncbi.nlm.nih.gov/pubmed/33060138
http://dx.doi.org/10.1534/genetics.120.303785

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