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Prenatal Opioid Exposure Enhances Responsiveness to Future Drug Reward and Alters Sensitivity to Pain: A Review of Preclinical Models and Contributing Mechanisms
The opioid crisis has resulted in an unprecedented number of neonates born with prenatal opioid exposure (POE); however, the long-term effects of POE on offspring behavior and neurodevelopment remain relatively unknown. The advantages and disadvantages of the various preclinical POE models developed...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Society for Neuroscience
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768284/ https://www.ncbi.nlm.nih.gov/pubmed/33060181 http://dx.doi.org/10.1523/ENEURO.0393-20.2020 |