The BRCA2 p.N372 H i.a.1342A>C Could Regulate the Sensitivity of Ovarian Cancer Cells to Platinum-Based Drugs

BACKGROUND AND OBJECTIVE: We have previously reported that BRCA2 N372 H i.a.1342A>C heterozygous variation presented in platinum-resistant patients. This study aimed to further investigate the mechanism of BRCA2 N372 H mutation in the development of platinum resistance in ovarian cancer. METHODS:...

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Detalles Bibliográficos
Autores principales: Du, Zhen-Hua, Xia, Yu, Yang, Qing, Gao, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768310/
https://www.ncbi.nlm.nih.gov/pubmed/33357097
http://dx.doi.org/10.1177/1533033820983289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768310/
https://www.ncbi.nlm.nih.gov/pubmed/33357097
http://dx.doi.org/10.1177/1533033820983289

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