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Perspective: Controlling Epidermal Terminal Differentiation with Transcriptional Bursting and RNA Bodies

The outer layer of the skin, the epidermis, is the principal barrier to the external environment: post-mitotic cells terminally differentiate to form a tough outer cornified layer of enucleate and flattened cells that confer the majority of skin barrier function. Nuclear degradation is required for...

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Detalles Bibliográficos
Autores principales: Wotherspoon, Duncan, Rogerson, Clare, O’Shaughnessy, Ryan F.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768391/
https://www.ncbi.nlm.nih.gov/pubmed/33291764
http://dx.doi.org/10.3390/jdb8040029