Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in Hepatocytes

BACKGROUND & AIMS: Systemic retinol (vitamin A) homeostasis is controlled by the liver, involving close collaboration between hepatocytes and hepatic stellate cells (HSCs). Genetic variants in retinol metabolism (PNPLA3 and HSD17B13) are associated with non-alcoholic fatty liver disease (NAFLD)...

Descripción completa

Detalles Bibliográficos
Autores principales: Saeed, Ali, Bartuzi, Paulina, Heegsma, Janette, Dekker, Daphne, Kloosterhuis, Niels, de Bruin, Alain, Jonker, Johan W., van de Sluis, Bart, Faber, Klaas Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768561/
https://www.ncbi.nlm.nih.gov/pubmed/32698042
http://dx.doi.org/10.1016/j.jcmgh.2020.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768561/
https://www.ncbi.nlm.nih.gov/pubmed/32698042
http://dx.doi.org/10.1016/j.jcmgh.2020.07.006

Ejemplares similares