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Early Signals of Vaccine-driven Perturbation Seen in Pneumococcal Carriage Population Genomic Data

BACKGROUND: Pneumococcal conjugate vaccines (PCVs) have reduced pneumococcal diseases globally. Pneumococcal genomic surveys elucidate PCV effects on population structure but are rarely conducted in low-income settings despite the high disease burden. METHODS: We undertook whole-genome sequencing (W...

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Detalles Bibliográficos
Autores principales: Chaguza, Chrispin, Heinsbroek, Ellen, Gladstone, Rebecca A, Tafatatha, Terence, Alaerts, Maaike, Peno, Chikondi, Cornick, Jennifer E, Musicha, Patrick, Bar-Zeev, Naor, Kamng’ona, Arox, Kadioglu, Aras, McGee, Lesley, Hanage, William P, Breiman, Robert F, Heyderman, Robert S, French, Neil, Everett, Dean B, Bentley, Stephen D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768739/
https://www.ncbi.nlm.nih.gov/pubmed/31094423
http://dx.doi.org/10.1093/cid/ciz404