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A dual role for α-synuclein in facilitation and depression of dopamine release from substantia nigra neurons in vivo
α-Synuclein is expressed at high levels at presynaptic terminals, but defining its role in the regulation of neurotransmission under physiologically relevant conditions has proven elusive. We report that, in vivo, α-synuclein is responsible for the facilitation of dopamine release triggered by actio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768743/ https://www.ncbi.nlm.nih.gov/pubmed/33273122 http://dx.doi.org/10.1073/pnas.2013652117 |