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Direct lysosome-based autophagy of lipid droplets in hepatocytes
Hepatocytes metabolize energy-rich cytoplasmic lipid droplets (LDs) in the lysosome-directed process of autophagy. An organelle-selective form of this process (macrolipophagy) results in the engulfment of LDs within double-membrane delimited structures (autophagosomes) before lysosomal fusion. Wheth...
Autores principales: | Schulze, Ryan J., Krueger, Eugene W., Weller, Shaun G., Johnson, Katherine M., Casey, Carol A., Schott, Micah B., McNiven, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768785/ https://www.ncbi.nlm.nih.gov/pubmed/33288726 http://dx.doi.org/10.1073/pnas.2011442117 |
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