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Effect of anti-IL17 and/or Rho-kinase inhibitor treatments on vascular remodeling induced by chronic allergic pulmonary inflammation

BACKGROUND AND AIMS: Expansion and morphological dysregulation of the bronchial vascular network occurs in asthmatic airways. Interleukin (IL) -17 and Rho-kinase (ROCK) are known to act in inflammation control and remodeling. Modulation of Rho-kinase proteins and IL-17 may be a promising approach fo...

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Detalles Bibliográficos
Autores principales: dos Santos, Tabata M., Righetti, Renato F., Rezende, Bianca G., Campos, Elaine C., Camargo, Leandro do N., Saraiva-Romanholo, Beatriz M., Fukuzaki, Silvia, Prado, Carla M., Leick, Edna A., Martins, Milton A., Tibério, Iolanda F. L. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768836/
https://www.ncbi.nlm.nih.gov/pubmed/33357114
http://dx.doi.org/10.1177/1753466620962665