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TDP-43–specific Autoantibody Decline in Patients With Amyotrophic Lateral Sclerosis

OBJECTIVE: We hypothesize alterations in the quality and quantity of anti–43-kDa TAR DNA-binding protein (TDP-43) naturally occurring autoantibodies (NAbs) in patients with amyotrophic lateral sclerosis (ALS); therefore, we assessed relative binding properties of anti–TDP-43 NAbs composite in plasma...

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Detalles Bibliográficos
Autores principales: Nielsen, Anne Kallehauge, Folke, Jonas, Owczarek, Sylwia, Svenstrup, Kirsten, Winge, Kristian, Pakkenberg, Bente, Aznar, Susana, Brudek, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768943/
https://www.ncbi.nlm.nih.gov/pubmed/33361387
http://dx.doi.org/10.1212/NXI.0000000000000937