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Polymeric Nanoparticles-Based Brain Delivery with Improved Therapeutic Efficacy of Ginkgolide B in Parkinson’s Disease

PURPOSE: Ginkgolide B (GB) is a terpene lactone derivative of Ginkgo biloba that is believed to function in a neuroprotective manner ideal for treating Parkinson’s disease (PD). Despite its promising therapeutic properties, GB has poor bioavailability following oral administration and cannot readily...

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Detalles Bibliográficos
Autores principales: Zhao, Yuying, Xiong, Sha, Liu, Piaoxue, Liu, Wei, Wang, Qun, Liu, Yao, Tan, Hanxu, Chen, Xiaojia, Shi, Xuguang, Wang, Qi, Chen, Tongkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769078/
https://www.ncbi.nlm.nih.gov/pubmed/33380795
http://dx.doi.org/10.2147/IJN.S272831