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Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins

As intracellular parasites, viruses hijack the host cell metabolic machinery for their replication. Among other cellular proteins, the DEAD-box (DDX) RNA helicases have been shown to be hijacked by coronaviruses and to participate in essential DDX-mediated viral replication steps. Human DDX RNA heli...

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Detalles Bibliográficos
Autores principales: Squeglia, Flavia, Romano, Maria, Ruggiero, Alessia, Maga, Giovanni, Berisio, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769135/
https://www.ncbi.nlm.nih.gov/pubmed/33381492
http://dx.doi.org/10.3389/fchem.2020.602162