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Regulation of neovasculogenesis in co-cultures of aortic adventitial fibroblasts and microvascular endothelial cells by cell-cell interactions and TGF-β/ALK5 signaling

Adventitial fibroblasts (AFs) are critical mediators of vascular remodeling. However, the contributions of AFs towards development of vasculature and the specific mechanisms by which these cells regulate physiological expansion of the vasa vasorum, the specialized microvasculature that supplies nutr...

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Detalles Bibliográficos
Autores principales: Scott, Rebecca A., Fowler, Eric W., Jia, Xinqiao, Kiick, Kristi L., Akins, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769260/
https://www.ncbi.nlm.nih.gov/pubmed/33370415
http://dx.doi.org/10.1371/journal.pone.0244243