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Rapid and robust patterns of spontaneous locomotor deficits in mouse models of Huntington’s disease

Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by severe disruption of cognitive and motor functions, including changes in posture and gait. A number of HD mouse models have been engineered that display behavioral and neuropathological features of the disease...

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Detalles Bibliográficos
Autores principales: Heikkinen, Taneli, Bragge, Timo, Bhattarai, Niina, Parkkari, Teija, Puoliväli, Jukka, Kontkanen, Outi, Sweeney, Patrick, Park, Larry C., Munoz-Sanjuan, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769440/
https://www.ncbi.nlm.nih.gov/pubmed/33370315
http://dx.doi.org/10.1371/journal.pone.0243052