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Rapid and robust patterns of spontaneous locomotor deficits in mouse models of Huntington’s disease
Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by severe disruption of cognitive and motor functions, including changes in posture and gait. A number of HD mouse models have been engineered that display behavioral and neuropathological features of the disease...
Autores principales: | Heikkinen, Taneli, Bragge, Timo, Bhattarai, Niina, Parkkari, Teija, Puoliväli, Jukka, Kontkanen, Outi, Sweeney, Patrick, Park, Larry C., Munoz-Sanjuan, Ignacio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769440/ https://www.ncbi.nlm.nih.gov/pubmed/33370315 http://dx.doi.org/10.1371/journal.pone.0243052 |
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