In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia

Achondroplasia is a rare genetic disorder caused by mutations in the Fibroblast Growth Factor receptor 3 (FGFR3). These mutations lead to aberrant increase of inhibitory signaling in proliferating chondrocytes at the growth plate. Recifercept is a potential treatment for this disease using a decoy a...

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Detalles Bibliográficos
Autores principales: Gonçalves, Diogo, Rignol, Guylène, Dellugat, Pierre, Hartmann, Guido, Sarrazy Garcia, Stephanie, Stavenhagen, Jeffrey, Santarelli, Luca, Gouze, Elvire, Czech, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769458/
https://www.ncbi.nlm.nih.gov/pubmed/33370388
http://dx.doi.org/10.1371/journal.pone.0244368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769458/
https://www.ncbi.nlm.nih.gov/pubmed/33370388
http://dx.doi.org/10.1371/journal.pone.0244368

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