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The dirty little secret of urate-lowering therapy: useless to stop chronic kidney disease progression and may increase mortality

Hyperuricaemia is frequent in chronic kidney disease (CKD). Observational studies have shown an association with adverse outcomes and acquired hyperuricaemia (meaning serum urate levels as low as 1.0 mg/dL) in animal models induces kidney injury. This evidence does not justify the widespread use of...

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Detalles Bibliográficos
Autores principales: Gonzalez-Martin, Guillermo, Cano, Jaime, Carriazo, Sol, Kanbay, Mehmet, Perez-Gomez, Maria Vanessa, Fernandez-Prado, Raul, Ortiz, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769546/
https://www.ncbi.nlm.nih.gov/pubmed/33391737
http://dx.doi.org/10.1093/ckj/sfaa236