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The dirty little secret of urate-lowering therapy: useless to stop chronic kidney disease progression and may increase mortality
Hyperuricaemia is frequent in chronic kidney disease (CKD). Observational studies have shown an association with adverse outcomes and acquired hyperuricaemia (meaning serum urate levels as low as 1.0 mg/dL) in animal models induces kidney injury. This evidence does not justify the widespread use of...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769546/ https://www.ncbi.nlm.nih.gov/pubmed/33391737 http://dx.doi.org/10.1093/ckj/sfaa236 |