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Cancer-associated fibroblasts and their influence on tumor immunity and immunotherapy

Fibroblasts play an essential role in organogenesis and the integrity of tissue architecture and function. Growth in most solid tumors is dependent upon remodeling ‘stroma’, composed of cancer-associated fibroblasts (CAFs) and extracellular matrix (ECM), which plays a critical role in tumor initiati...

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Detalles Bibliográficos
Autores principales: Barrett, Richard Lee, Puré, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769568/
https://www.ncbi.nlm.nih.gov/pubmed/33370234
http://dx.doi.org/10.7554/eLife.57243