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Cancer-associated fibroblasts and their influence on tumor immunity and immunotherapy
Fibroblasts play an essential role in organogenesis and the integrity of tissue architecture and function. Growth in most solid tumors is dependent upon remodeling ‘stroma’, composed of cancer-associated fibroblasts (CAFs) and extracellular matrix (ECM), which plays a critical role in tumor initiati...
Autores principales: | Barrett, Richard Lee, Puré, Ellen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769568/ https://www.ncbi.nlm.nih.gov/pubmed/33370234 http://dx.doi.org/10.7554/eLife.57243 |
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