Protective efficacy of an attenuated Mtb ΔLprG vaccine in mice

Bacille Calmette-Guerin (BCG), an attenuated whole cell vaccine based on Mycobacterium bovis, is the only licensed vaccine against Mycobacterium tuberculosis (Mtb), but its efficacy is suboptimal and it fails to protect against pulmonary tuberculosis. We previously reported that Mtb lacking the viru...

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Detalles Bibliográficos
Autores principales: Martinot, Amanda J., Blass, Eryn, Yu, Jingyou, Aid, Malika, Mahrokhian, Shant H., Cohen, Sara B., Plumlee, Courtney R., Larocca, Rafael A., Siddiqi, Noman, Wakabayashi, Shoko, Gardner, Michelle, Audette, Rebecca, Devorak, Anne, Urdahl, Kevin B., Rubin, Eric J., Barouch, Dan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769599/
https://www.ncbi.nlm.nih.gov/pubmed/33315936
http://dx.doi.org/10.1371/journal.ppat.1009096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769599/
https://www.ncbi.nlm.nih.gov/pubmed/33315936
http://dx.doi.org/10.1371/journal.ppat.1009096

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