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Protective efficacy of an attenuated Mtb ΔLprG vaccine in mice
Bacille Calmette-Guerin (BCG), an attenuated whole cell vaccine based on Mycobacterium bovis, is the only licensed vaccine against Mycobacterium tuberculosis (Mtb), but its efficacy is suboptimal and it fails to protect against pulmonary tuberculosis. We previously reported that Mtb lacking the viru...
Autores principales: | Martinot, Amanda J., Blass, Eryn, Yu, Jingyou, Aid, Malika, Mahrokhian, Shant H., Cohen, Sara B., Plumlee, Courtney R., Larocca, Rafael A., Siddiqi, Noman, Wakabayashi, Shoko, Gardner, Michelle, Audette, Rebecca, Devorak, Anne, Urdahl, Kevin B., Rubin, Eric J., Barouch, Dan H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769599/ https://www.ncbi.nlm.nih.gov/pubmed/33315936 http://dx.doi.org/10.1371/journal.ppat.1009096 |
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