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A viral guide RNA delivery system for CRISPR-based transcriptional activation and heritable targeted DNA demethylation in Arabidopsis thaliana

Plant RNA viruses are used as delivery vectors for their high level of accumulation and efficient spread during virus multiplication and movement. Utilizing this concept, several viral-based guide RNA delivery platforms for CRISPR-Cas9 genome editing have been developed. The CRISPR-Cas9 system has a...

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Detalles Bibliográficos
Autores principales: Ghoshal, Basudev, Vong, Brandon, Picard, Colette L., Feng, Suhua, Tam, Janet M., Jacobsen, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769603/
https://www.ncbi.nlm.nih.gov/pubmed/33315895
http://dx.doi.org/10.1371/journal.pgen.1008983