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S100A4+ macrophages facilitate zika virus invasion and persistence in the seminiferous tubules via interferon-gamma mediation

Testicular invasion and persistence are features of Zika virus (ZIKV), but their mechanisms are still unknown. Here, we showed that S100A4+ macrophages, a myeloid macrophage subpopulation with susceptibility to ZIKV infection, facilitated ZIKV invasion and persistence in the seminiferous tubules. In...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Wu, Yan-Hua, Liu, Shuang-Qing, Sheng, Zi-Yang, Zhen, Zi-Da, Gao, Rui-Qi, Cui, Xiao-Yun, Fan, Dong-Ying, Qin, Zhi-Hai, Zheng, Ai-Hua, Wang, Pei-Gang, An, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769614/
https://www.ncbi.nlm.nih.gov/pubmed/33315931
http://dx.doi.org/10.1371/journal.ppat.1009019