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Fluvastatin-Pretreated Donor Cells Attenuated Murine aGVHD by Balancing Effector T Cell Distribution and Function under the Regulation of KLF2

Prevention of acute graft-versus-host disease (aGVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is still to be explored. Statins are potent immunomodulatory agents that hold promise as novel and safe agents for aGVHD prophylaxis, yet the controversial effect and regulatory...

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Detalles Bibliográficos
Autores principales: Zhao, Kai, Tian, Yu, Wang, Junjie, Chen, Chong, Pan, Bin, Yan, Zhiling, Zhu, Shengyun, Xu, Kailin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769635/
https://www.ncbi.nlm.nih.gov/pubmed/33415155
http://dx.doi.org/10.1155/2020/7619849