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Deep Sequencing of B Cell Receptor Repertoires From COVID-19 Patients Reveals Strong Convergent Immune Signatures

Deep sequencing of B cell receptor (BCR) heavy chains from a cohort of 31 COVID-19 patients from the UK reveals a stereotypical naive immune response to SARS-CoV-2 which is consistent across patients. Clonal expansion of the B cell population is also observed and may be the result of memory bystande...

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Detalles Bibliográficos
Autores principales: Galson, Jacob D., Schaetzle, Sebastian, Bashford-Rogers, Rachael J. M., Raybould, Matthew I. J., Kovaltsuk, Aleksandr, Kilpatrick, Gavin J., Minter, Ralph, Finch, Donna K., Dias, Jorge, James, Louisa K., Thomas, Gavin, Lee, Wing-Yiu Jason, Betley, Jason, Cavlan, Olivia, Leech, Alex, Deane, Charlotte M., Seoane, Joan, Caldas, Carlos, Pennington, Daniel J., Pfeffer, Paul, Osbourn, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769841/
https://www.ncbi.nlm.nih.gov/pubmed/33384691
http://dx.doi.org/10.3389/fimmu.2020.605170