Extracellular vesicles containing ACE2 efficiently prevent infection by SARS‐CoV‐2 Spike protein‐containing virus

SARS‐CoV‐2 entry is mediated by binding of the spike protein (S) to the surface receptor ACE2 and subsequent priming by host TMPRSS2 allowing membrane fusion. Here, we produced extracellular vesicles (EVs) exposing ACE2 and demonstrate that ACE2‐EVs are efficient decoys for SARS‐CoV‐2 S protein‐cont...

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Detalles Bibliográficos
Autores principales: Cocozza, Federico, Névo, Nathalie, Piovesana, Ester, Lahaye, Xavier, Buchrieser, Julian, Schwartz, Olivier, Manel, Nicolas, Tkach, Mercedes, Théry, Clotilde, Martin‐Jaular, Lorena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769856/
https://www.ncbi.nlm.nih.gov/pubmed/33391636
http://dx.doi.org/10.1002/jev2.12050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769856/
https://www.ncbi.nlm.nih.gov/pubmed/33391636
http://dx.doi.org/10.1002/jev2.12050

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