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Astrocyte HIV-1 Tat Differentially Modulates Behavior and Brain MMP/TIMP Balance During Short and Prolonged Induction in Transgenic Mice

Despite effective antiretroviral therapy (ART), mild forms of HIV-associated neurocognitive disorders (HAND) continue to afflict approximately half of all people living with HIV (PLWH). As PLWH age, HIV-associated inflammation perturbs the balance between brain matrix metalloproteinases (MMPs) and t...

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Detalles Bibliográficos
Autores principales:	Joshi, Chaitanya R., Stacy, Satomi, Sumien, Nathalie, Ghorpade, Anuja, Borgmann, Kathleen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769877/ https://www.ncbi.nlm.nih.gov/pubmed/33384653 http://dx.doi.org/10.3389/fneur.2020.593188

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