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Myosin Va Brain-Specific Mutation Alters Mouse Behavior and Disrupts Hippocampal Synapses

Myosin Va (MyoVa) is a plus-end filamentous-actin motor protein that is highly and broadly expressed in the vertebrate body, including in the nervous system. In excitatory neurons, MyoVa transports cargo toward the tip of the dendritic spine, where the postsynaptic density (PSD) is formed and mainta...

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Detalles Bibliográficos
Autores principales: Pandian, Swarna, Zhao, Jian-Ping, Murata, Yasunobu, Bustos, Fernando J., Tunca, Cansu, Almeida, Ramiro D., Constantine-Paton, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769881/
https://www.ncbi.nlm.nih.gov/pubmed/33229412
http://dx.doi.org/10.1523/ENEURO.0284-20.2020