Cargando…

Myosin Va Brain-Specific Mutation Alters Mouse Behavior and Disrupts Hippocampal Synapses

Myosin Va (MyoVa) is a plus-end filamentous-actin motor protein that is highly and broadly expressed in the vertebrate body, including in the nervous system. In excitatory neurons, MyoVa transports cargo toward the tip of the dendritic spine, where the postsynaptic density (PSD) is formed and mainta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pandian, Swarna, Zhao, Jian-Ping, Murata, Yasunobu, Bustos, Fernando J., Tunca, Cansu, Almeida, Ramiro D., Constantine-Paton, Martha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2020
Materias:	Research Article: New Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769881/ https://www.ncbi.nlm.nih.gov/pubmed/33229412 http://dx.doi.org/10.1523/ENEURO.0284-20.2020

Ejemplares similares

Removal of a partial genomic duplication restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer
por: Bustos, Fernando J., et al.
Publicado: (2023)

Impairing the function of MLCK, myosin Va or myosin Vb disrupts Rhinovirus B14 replication
por: Real-Hohn, Antonio, et al.
Publicado: (2017)

Properties of Individual Hippocampal Synapses Influencing NMDA-Receptor Activation by Spontaneous Neurotransmission
por: Metzbower, Sarah R., et al.
Publicado: (2019)

Plasticity of NMDA Receptors at Ventral Hippocampal Synapses in the Infralimbic Cortex Regulates Cued Fear
por: Soler-Cedeño, Omar, et al.
Publicado: (2019)

Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density
por: Rao, Mala V., et al.
Publicado: (2002)

The Mixed-Lineage Kinase Inhibitor URMC-099 Protects Hippocampal Synapses in Experimental Autoimmune Encephalomyelitis
por: Bellizzi, Matthew J., et al.
Publicado: (2018)

The Nogo Receptor Ligand LGI1 Regulates Synapse Number and Synaptic Activity in Hippocampal and Cortical Neurons
por: Thomas, Rhalena A., et al.
Publicado: (2018)

The disconnect2 mutation disrupts the tjp1b gene that is required for electrical synapse formation
por: Michel, Jennifer Carlisle, et al.
Publicado: (2022)

Examining Hippocampal Mossy Fiber Synapses by 3D Electron Microscopy in Wildtype and Kirrel3 Knockout Mice
por: Martin, E. Anne, et al.
Publicado: (2017)

A mutation in switch I alters the load-dependent kinetics of myosin Va
por: Marang, Christopher, et al.
Publicado: (2023)

MST3 Kinase Phosphorylates TAO1/2 to Enable Myosin Va Function in Promoting Spine Synapse Development
por: Ultanir, Sila K., et al.
Publicado: (2014)

Axonal Type III Nrg1 Controls Glutamate Synapse Formation and GluA2 Trafficking in Hippocampal-Accumbens Connections
por: Zhong, Chongbo, et al.
Publicado: (2017)

Leptin Induces a Novel Form of NMDA Receptor-Dependent LTP at Hippocampal Temporoammonic-CA1 Synapses1,2,3
por: Luo, Xiao, et al.
Publicado: (2015)

Local Design Principles at Hippocampal Synapses Revealed by an Energy-Information Trade-Off
por: Mahajan, Gaurang, et al.
Publicado: (2020)

Role of myosin Va in purinergic vesicular neurotransmission in the gut
por: Chaudhury, Arun, et al.
Publicado: (2012)

Myosin Va interacts with the exosomal protein spermine synthase
por: Dolce, Luciano G., et al.
Publicado: (2019)

Myosin Va and spermine synthase: partners in exosome transport
por: Timson, David J.
Publicado: (2019)

Decreased Reactive Oxygen Species Signaling Alters Glutamate Receptor Transport to Synapses in C. elegans AVA Neurons
por: Doser, Rachel L, et al.
Publicado: (2022)

Sleep Deprivation Disrupts Acquisition of Contextual Fear Extinction by Affecting Circadian Oscillation of Hippocampal-Infralimbic proBDNF
por: Sun, Wei, et al.
Publicado: (2019)

Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons
por: Sørensen, Andreas T., et al.
Publicado: (2018)

Role of Myosin Va in the Plasticity of the Vertebrate Neuromuscular Junction In Vivo
por: Röder, Ira Verena, et al.
Publicado: (2008)

Identification and characterization of multiple novel Rab–myosin Va interactions
por: Lindsay, Andrew J., et al.
Publicado: (2013)

Deletion of the Mouse Homolog of CACNA1C Disrupts Discrete Forms of Hippocampal-Dependent Memory and Neurogenesis within the Dentate Gyrus
por: Temme, Stephanie J., et al.
Publicado: (2016)

Western High-Fat Diet Consumption during Adolescence Increases Susceptibility to Traumatic Stress while Selectively Disrupting Hippocampal and Ventricular Volumes
por: Kalyan-Masih, Priya, et al.
Publicado: (2016)

Heterozygous Dab1 Null Mutation Disrupts Neocortical and Hippocampal Development
por: Honda, Takao, et al.
Publicado: (2023)

A role for Arabidopsis myosins in sugar-induced hypocotyl elongation
por: Olatunji, Damilola, et al.
Publicado: (2020)

Melanophilin and myosin Va track the microtubule plus end on EB1
por: Wu, Xufeng S., et al.
Publicado: (2005)

Participation of Myosin Va and Pka Type I in the Regeneration of Neuromuscular Junctions
por: Röder, Ira Verena, et al.
Publicado: (2012)

Interactions between Leishmania braziliensis and Macrophages Are Dependent on the Cytoskeleton and Myosin Va
por: Azevedo, Elisama, et al.
Publicado: (2012)

Myosin-Va Transports the Endoplasmic Reticulum into the Dendritic Spines of Purkinje Neurons
por: Wagner, Wolfgang, et al.
Publicado: (2010)

Absence of Platelet Phenotype in Mice Lacking the Motor Protein Myosin Va
por: Harper, Matthew T., et al.
Publicado: (2013)

Myosin-Va Contributes to Manifestation of Malignant-Related Properties in Melanoma Cells
por: Alves, Cleidson P., et al.
Publicado: (2013)

Tropomyosin isoforms bias actin track selection by vertebrate myosin Va
por: Sckolnick, Maria, et al.
Publicado: (2016)

Autoinhibition and activation mechanisms revealed by the triangular-shaped structure of myosin Va
por: Niu, Fengfeng, et al.
Publicado: (2022)

Microglia Enhance Synapse Activity to Promote Local Network Synchronization
por: Akiyoshi, Ryohei, et al.
Publicado: (2018)

Introduction of Tau Oligomers into Cortical Neurons Alters Action Potential Dynamics and Disrupts Synaptic Transmission and Plasticity
por: Hill, Emily, et al.
Publicado: (2019)

Shaping of Signal Transmission at the Photoreceptor Synapse by EAAT2 Glutamate Transporters
por: Niklaus, Stephanie, et al.
Publicado: (2017)

T Lymphocyte Myosin IIA is Required for Maturation of the Immunological Synapse
por: Kumari, Sudha, et al.
Publicado: (2012)

Flexural Stiffness of Myosin Va Subdomains as Measured from Tethered Particle Motion
por: Michalek, Arthur J., et al.
Publicado: (2015)

Specific Disruption of Hippocampal Mossy Fiber Synapses in a Mouse Model of Familial Alzheimer's Disease
por: Wilke, Scott A., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_oeff1fr8cd9t4mvgr4rmcohqh3