MFSD12 mediates the import of cysteine into melanosomes and lysosomes

Dozens of genes contribute to the vast variation in human pigmentation. Many of these encode proteins that localize to the melanosome, the lysosome-related organelle that synthesizes pigment, but have unclear functions (1,2). Here, we describe the MelanoIP method for rapidly isolating melanosomes an...

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Detalles Bibliográficos
Autores principales: Adelmann, Charles H., Traunbauer, Anna K., Chen, Brandon, Condon, Kendall J., Chan, Sze Ham, Kunchok, Tenzin, Lewis, Caroline A., Sabatini, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770032/
https://www.ncbi.nlm.nih.gov/pubmed/33208952
http://dx.doi.org/10.1038/s41586-020-2937-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770032/
https://www.ncbi.nlm.nih.gov/pubmed/33208952
http://dx.doi.org/10.1038/s41586-020-2937-x

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