A New Metric Quantifying Chemical and Biological Property of Small Molecule Metabolites and Drugs

One prominent class of drugs is chemical small molecules (CSMs), but the majority of CSMs are of very low druggable potential. Therefore, it is quite important to predict drug-related properties (druggable properties) for candidate CSMs. Currently, a number of druggable properties (e.g., logP and pK...

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Detalles Bibliográficos
Autores principales: Huang, Chuanbo, Zhou, Yuan, Yang, Jichun, Cui, Qinghua, Li, Yanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770129/
https://www.ncbi.nlm.nih.gov/pubmed/33385011
http://dx.doi.org/10.3389/fmolb.2020.594800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770129/
https://www.ncbi.nlm.nih.gov/pubmed/33385011
http://dx.doi.org/10.3389/fmolb.2020.594800

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