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Factor H Autoantibodies and Complement-Mediated Diseases

Factor H (FH), a member of the regulators-of-complement-activation (RCA) family of proteins, circulates in human plasma at concentrations of 180–420 mg/L where it controls the alternative pathway (AP) of complement in the fluid phase and on cell surfaces. When the regulatory function of FH is impair...

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Detalles Bibliográficos
Autores principales: Zhang, Yuzhou, Ghiringhelli Borsa, Nicolo, Shao, Dingwu, Dopler, Arthur, Jones, Michael B., Meyer, Nicole C., Pitcher, Gabriella R., Taylor, Amanda O., Nester, Carla M., Schmidt, Christoph Q., Smith, Richard J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770156/
https://www.ncbi.nlm.nih.gov/pubmed/33384694
http://dx.doi.org/10.3389/fimmu.2020.607211