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Identification of Pro-Fibrotic Macrophage Populations by Single-Cell Transcriptomic Analysis in West Highland White Terriers Affected With Canine Idiopathic Pulmonary Fibrosis

Canine idiopathic pulmonary fibrosis (CIPF) affects old dogs from the West Highland white terrier (WHWT) breed and mimics idiopathic pulmonary fibrosis (IPF) in human. The disease results from deposition of fibrotic tissue in the lung parenchyma causing respiratory failure. Recent studies in IPF usi...

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Detalles Bibliográficos
Autores principales: Fastrès, Aline, Pirottin, Dimitri, Fievez, Laurence, Tutunaru, Alexandru-Cosmin, Bolen, Géraldine, Merveille, Anne-Christine, Marichal, Thomas, Desmet, Christophe J., Bureau, Fabrice, Clercx, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770158/
https://www.ncbi.nlm.nih.gov/pubmed/33384697
http://dx.doi.org/10.3389/fimmu.2020.611749