Effects of suppressing bioavailability of insulin‐like growth factor on age‐associated intervertebral disc degeneration

Suppression of the insulin‐like growth factor‐1 (IGF‐1) signaling pathway reduces age‐related disorders and increases lifespan across species, making the IGF‐1 pathway a key regulator of aging. Previous in vitro intervertebral disc cell studies have reported the pro‐anabolic effect of exogenously ad...

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Detalles Bibliográficos
Autores principales: Kritschil, Rebecca, Zhang, Zhongying, Lei, Changbin, Zhong, Jiongbiao, Dong, Qing, Lee, Joon, Conover, Cheryl A., Sowa, Gwendolyn, Vallejo, Abbe N., Vo, Nam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Special Issue PSRS Conference 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770198/
https://www.ncbi.nlm.nih.gov/pubmed/33392450
http://dx.doi.org/10.1002/jsp2.1112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770198/
https://www.ncbi.nlm.nih.gov/pubmed/33392450
http://dx.doi.org/10.1002/jsp2.1112

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