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Verteporfin treatment controls morphology, phenotype, and global gene expression for cells of the human nucleus pulposus

Cells of the nucleus pulposus (NP) are essential contributors to extracellular matrix synthesis and function of the intervertebral disc. With age and degeneration, the NP becomes stiffer and more dehydrated, which is associated with a loss of phenotype and biosynthetic function for its resident NP c...

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Detalles Bibliográficos
Autores principales: Fearing, Bailey V., Speer, Julie E., Jing, Liufang, Kalathil, Aravind, P. Kelly, Michael, M. Buchowski, Jacob, P. Zebala, Lukas, Luhmann, Scott, C. Gupta, Munish, A. Setton, Lori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770208/
https://www.ncbi.nlm.nih.gov/pubmed/33392449
http://dx.doi.org/10.1002/jsp2.1111