Determination and pharmacokinetic analysis of ticarcillin disodium–clavulanate potassium for injection in rat plasma by UPLC-ESI-MS/MS

OBJECTIVE: To establish a specific and rapid ultra-high-performance liquid chromatography–electrospray ionization–tandem mass spectrometry (UPLC-ESI-MS/MS) method for measuring ticarcillin and clavulanate levels in rat plasma. METHODS: A Waters ACQUITY BEH C18 column (50 mm × 2.1 mm, 1.7 μm) and SCI...

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Detalles Bibliográficos
Autores principales: Wang, Moli, Gao, Yanxia, Liu, Xueli, Zhang, Jing, Wang, Qiang, Chang, Junshan, Zhang, Lantong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Meta Analysis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770263/
https://www.ncbi.nlm.nih.gov/pubmed/33356736
http://dx.doi.org/10.1177/0300060520967822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770263/
https://www.ncbi.nlm.nih.gov/pubmed/33356736
http://dx.doi.org/10.1177/0300060520967822

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